Should the esophageal balloon catheter be deployed to personalize ventilation of ARDS? Authors’ reply - Takeaways - MDSpire
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Authors’ Response: Can Esophageal Balloon Catheters Guide Personalized Ventilation in ARDS?

  • By

  • John J. Marini

  • Niall D. Ferguson

  • Daniel Talmor

  • October 15, 2026

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  • 1

    The authors appreciated Barrau and colleagues’ constructive commentary.

  • 2

    Massive obesity primarily affects chest wall mechanics through mass loading and a rightward displacement of the pressure–volume relationship.

  • 3

    Mass loading raises the pleural pressure required for chest wall expansion across the tidal range.

  • 4

    Mass loading also raises the pressure used to calculate bedside elastance.

  • 5

    These effects have implications for lung recruitment, effective lung protection, and esophageal pressure measurement in ARDS management.

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