Maternal Cardiovascular Health During Pregnancy and Offspring Developmental Delay

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Developmental delay affects approximately 15% of US youths and contributes to various social and educational challenges.
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Maternal cardiovascular health (CVH) during pregnancy is assessed using the Life's Essential 8 (LE8) framework.
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The study aims to examine the association between maternal CVH during pregnancy and developmental delay in offspring at 4 years of age.
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CVH was evaluated through metrics including diet, physical activity, nicotine exposure, sleep health, BMI, blood lipids, blood glucose, and blood pressure.
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Developmental delay in offspring was assessed using the Ages and Stages Questionnaire, Third Edition (ASQ-3), at 4 years of age.

Jama Network Open

by Hisashi Ohseto, Mami Ishikuro, Geng Chen, Ippei Takahashi, Genki Shinoda, Aoi Noda, Keiko Murakami, Masatsugu Orui, Masato Takase, Noriyuki Iwama, Masahiro Kikuya, Hirohito Metoki, Atsushi Hozawa, Taku Obara, Shinichi Kuriyama
June 23, 2026

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