Link Between Obstructive Sleep Apnea and Nasopharyngeal Carcinoma

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The study investigates the association between obstructive sleep apnea (OSA) and nasopharyngeal carcinoma (NPC) using a large population-based case-control design.
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Data was sourced from the Longitudinal Health Insurance Database 2010, including 3,235 NPC patients and 12,940 matched controls.
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Prior OSA prevalence was significantly higher in the NPC group compared to controls (2.07% vs. 1.51%, p = 0.023).
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After adjusting for confounders, pre-existing OSA was associated with increased odds of developing NPC (adjusted OR = 1.42, 95% CI = 1.07, 1.89).
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The association between OSA and NPC was statistically significant in males but not in females, possibly due to smaller sample size.

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