Association of Preoperative Inflammatory Markers With Preoperative Anxiety and Emergence Agitation in Children - Takeaways - MDSpire
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Link Between Preoperative Inflammatory Biomarkers, Anxiety Levels, and Emergence Agitation in Pediatric Patients

  • By

  • Nezahat Merve Ata Soylu

  • Zehra Hatipoglu

  • Ersel Gulec

  • Mediha Turktan

  • Nurefsan Sadıkoglu

  • Yusuf Kemal Arslan

  • Dilek Ozcengiz

  • June 18, 2026

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  • 1

    Preoperative anxiety affects up to 65% of pediatric patients and is linked to emergence agitation (EA) post-anesthesia.

  • 2

    Emergence agitation can occur in 0.25% to 90.5% of children within 30 minutes after anesthesia, characterized by restlessness and agitation.

  • 3

    Neuroinflammatory mediators may connect preoperative anxiety to postoperative neurocognitive dysfunction, including EA.

  • 4

    The study aims to investigate the relationship between preoperative inflammatory markers and EA, as well as preoperative anxiety.

  • 5

    The study includes 350 pediatric patients aged 5-12 years and evaluates hemogram-derived inflammatory markers for associations with EA.

Original Source(s)

Association of Preoperative Inflammatory Markers With Preoperative Anxiety and Emergence Agitation in Children

  • by Nezahat Merve Ata Soylu, Zehra Hatipoglu, Ersel Gulec, Mediha Turktan, Nurefsan Sadıkoglu, Yusuf Kemal Arslan, Dilek Ozcengiz

  • June 18, 2026

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