One in Ten Develop Seroma - Takeaways - MDSpire

One in Ten Develop Seroma

  • By

  • Jess Allerton

  • February 17, 2026

  • 2 min

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  • 1

    Seroma developed in 11% of patients after parotidectomy in a study of 527 cases published in Frontiers in Surgery.

  • 2

    The median onset of seroma was 4 days post-drain removal, with a median resolution time of 17 days.

  • 3

    Independent risk factors for seroma included anterior tumor location, larger tumor size, higher BMI, and facelift-type incision.

  • 4

    Persistent seroma occurred in 4% of patients, defined as fluid lasting over 14 days or requiring multiple aspirations.

  • 5

    The study suggests that tumor characteristics and incision type may be more predictive of seroma than surgical extent.

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