A primary hepatopancreatic cell platform enables cellular dissection of glucose metabolism and endocrine-metabolic regulation in Litopenaeus vannamei - Takeaways - MDSpire
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

Establishment of a Primary Hepatopancreatic Cell Model for Investigating Glucose Metabolism and Endocrine Regulation in Litopenaeus vannamei

  • By

  • Xiaowei Song

  • Zijie Liu

  • Jiawei Liu

  • Su Liu

  • Lin Song

  • Hu Duan

  • Yi Gao

  • August 21, 2026

Share

  • 1

    A primary hepatopancreatic cell model was established from Litopenaeus vannamei to study glucose metabolism and endocrine regulation.

  • 2

    The isolated cells maintained key characteristics and viability during short-term culture for functional assays.

  • 3

    Exogenous glucose increased glucose transport and glycolysis-related transcription while suppressing gluconeogenesis-related genes.

  • 4

    Insulin exposure enhanced glucose accumulation and transcriptional activity, indicating preserved hormone-responsive properties.

  • 5

    The study provides a valuable platform for investigating nutrient sensing and metabolic regulation in crustaceans.

Original Source(s)

A primary hepatopancreatic cell platform enables cellular dissection of glucose metabolism and endocrine-metabolic regulation in Litopenaeus vannamei

  • by Xiaowei Song, Zijie Liu, Jiawei Liu, Su Liu, Lin Song, Hu Duan, Yi Gao

  • August 21, 2026

Related Content

Publisher Correction: Enhancing Postoperative Outcomes After Metabolic Bariatric Surgery: a Pilot Study of Inhibitory Control Training, Transcranial Direct Current Stimulation and Psychosocial Aftercare

How much of a cancer drug is too much? Patients, researchers challenge FDA-approved dosages

“There is incredible uncertainty in drug dosing.”

Can GH therapy improve final height after HCT?

Growth gains continued beyond the first year of treatment, while irradiation and other transplant-related factors influenced response.