Colonic resection or self-expanding metal stents for obstructive left colon cancer: results of a national multicenter prospective cohort study (CROSCO-1) - Takeaways - MDSpire

Colonic resection or self-expanding metal stents for obstructive left colon cancer: results of a national multicenter prospective cohort study (CROSCO-1)

  • By

  • Alessio Giordano

  • Manuela Mastronardi

  • Paola Fugazzola

  • Giulia Montori

  • Ferdinando Agresta

  • Jacopo Martellucci

  • Fausto Catena

  • Federico Coccolini

  • Gabriele Anania

  • Gianluca Costa

  • Vincenzo Bottino

  • Nicola Cillara

  • Paolo Prosperi

  • Carlo Bergamini

  • Mauro Podda

  • June 3, 2026

  • 0 min

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  • 1

    Colorectal cancer (CRC) has a global incidence of 1.4 million new cases annually, with large bowel obstruction occurring in 8–13% of patients.

  • 2

    Self-expanding metallic stents (SEMS) have been used since the mid-1990s for managing malignant colonic obstruction, offering an alternative to surgery.

  • 3

    The CROSCO-1 study is a multicenter, prospective cohort study comparing SEMS placement with emergency surgery for obstructive left-sided colon cancer.

  • 4

    Eligible patients included adults with left-sided malignant colonic obstruction, confirmed by CT, and without distant metastases or peritoneal carcinomatosis.

  • 5

    The primary outcome of the study is the stoma rate at one year post-tumor resection, with secondary outcomes including morbidity, mortality, and quality of life.

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