Recent and Cumulative Cannabis Use and Sleep in Middle-Aged Adults - Takeaways - MDSpire
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Recent and Long-Term Cannabis Use in Relation to Sleep Among Middle-Aged Adults

  • By

  • Thanh-Huyen T. Vu

  • Kristen L. Knutson

  • Reto Auer

  • Julian Jakob

  • Donald M. Lloyd-Jones

  • Mercedes R. Carnethon

  • October 9, 2026

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  • 1

    This CARDIA cohort study examined associations of cumulative and recent cannabis use with objective and subjective sleep outcomes in middle-aged adults.

  • 2

    The analysis included 1266 participants; objective-sleep analyses included 891, and subjective-sleep analyses included 1128.

  • 3

    Participants reported nonmedical cannabis use at repeated examinations over 35 years, and cumulative exposure was calculated in cannabis-years.

  • 4

    Objective sleep was assessed with 7-day wrist actigraphy, measuring sleep duration, sleep percentage, fragmentation, and wakefulness after sleep onset.

  • 5

    Subjective sleep quality was measured with the Pittsburgh Sleep Quality Index, with scores greater than 5 classified as poor sleep quality.

Original Source(s)

Recent and Cumulative Cannabis Use and Sleep in Middle-Aged Adults

  • by Thanh-Huyen T. Vu, Kristen L. Knutson, Reto Auer, Julian Jakob, Donald M. Lloyd-Jones, Mercedes R. Carnethon

  • October 9, 2026

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