MR-guided Laser Interstitial Thermal Therapy mesencephalotomy for medically intractable malignant pain

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MR-guided Laser Interstitial Thermal Therapy (MRgLITT) mesencephalotomy targets pain pathways to manage intractable malignant pain.
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The procedure was performed on a 47-year-old male with metastatic melanoma and severe, treatment-resistant pain.
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MRgLITT offers real-time imaging guidance, allowing precise lesioning with minimal invasiveness compared to historical techniques.
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Postoperatively, the patient experienced significant pain relief, with visual analog scale scores decreasing from > 7 to < 3.
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This case highlights the need for multidisciplinary approaches in selecting patients for MRgLITT mesencephalotomy.

Acta Neurochirurgica

by Mickael Aubignat, Jean-Marc Constans, Martial Ouendo, Jean-Philippe Arnault, Claire Josse, Christine Desenclos, Michel Lefranc
May 2, 2025

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