Role of the frontal aslant tract in language preservation and recovery after surgery: a multicenter analysis of patients with left frontal glioma - Takeaways - MDSpire
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Impact of the Frontal Aslant Tract on Language Function Maintenance and Recovery Post-Surgery: A Multicenter Study of Patients with Left Frontal Gliomas

  • By

  • L. F. Salvati

  • R. De Marco

  • F. Balletti

  • A. Morello

  • A. Gatto

  • A. Leocata

  • P. Fiaschi

  • S. Caneva

  • B. Cagetti

  • M. Truffelli

  • F. Bruno

  • A. Tabano

  • G. Zona

  • F. Cofano

  • R. Rudà

  • D. Garbossa

  • A. Bianconi

  • July 3, 2026

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  • 1

    The study evaluated the impact of the frontal aslant tract (FAT) on language function in patients undergoing surgery for left frontal gliomas.

  • 2

    A total of 51 patients were recruited, with maximal tumor resection achieved in 58.8% of cases, and 56.9% experienced postoperative language worsening.

  • 3

    Surgical manipulation of the FAT was linked to language impairment, particularly the volume of fibers resected and the specific FAT segment involved.

  • 4

    Resection of the middle segment of the FAT was associated with immediate language worsening and poor long-term outcomes.

  • 5

    A FAT resection volume of at least 0.5 cm3 was identified as a significant predictor of persistent language deficits post-surgery.

Original Source(s)

Role of the frontal aslant tract in language preservation and recovery after surgery: a multicenter analysis of patients with left frontal glioma

  • by L. F. Salvati, R. De Marco, F. Balletti, A. Morello, A. Gatto, A. Leocata, P. Fiaschi, S. Caneva, B. Cagetti, M. Truffelli, F. Bruno, A. Tabano, G. Zona, F. Cofano, R. Rudà, D. Garbossa, A. Bianconi

  • July 3, 2026

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