Assessing multiple-choice question quality in internal medicine: a comparative analysis of three large language models against expert consensus - Takeaways - MDSpire

Assessing multiple-choice question quality in internal medicine: a comparative analysis of three large language models against expert consensus

  • By

  • Mevlüt Okan Aydin

  • Belkıs Nihan Coşkun

  • İbrahim Hamal

  • July 9, 2026

  • 0 min

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  • 1

    The study evaluated 85 multiple-choice questions from an internal medicine clerkship using three large language models and expert consensus.

  • 2

    Gemini and Claude showed moderate agreement with experts for cognitive level classification, while Llama demonstrated lower agreement.

  • 3

    Claude and Gemini achieved almost perfect agreement on detecting negatively worded stems and substantial agreement on inconsistent numerical data.

  • 4

    Weak agreement was observed for alignment with learning outcomes across all models, indicating limitations in LLM evaluations.

  • 5

    The findings suggest a hybrid approach combining LLM-assisted screening with human expertise may optimize item quality assurance.

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