Retrospective Analysis of Kampo Medicine's Role in Mitigating Endocrine Therapy Side Effects in Breast Cancer Patients: A Pilot Investigation - Takeaways - MDSpire

Retrospective Analysis of Kampo Medicine's Role in Mitigating Endocrine Therapy Side Effects in Breast Cancer Patients: A Pilot Investigation

  • By

  • Shin Takayama

  • Atsuhiko Furuta

  • Haruhiko Shindo

  • Ryutaro Arita

  • Kaolu Sato

  • Tadashi Ishii

  • February 26, 2026

  • 0 min

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  • 1

    Kampo medicines effectively alleviate menopause-like symptoms in breast cancer patients undergoing long-term endocrine therapy.

  • 2

    A retrospective study analyzed 53 patients, revealing that 75% reported significant symptom relief after 6 months of Kampo treatment.

  • 3

    Keishibukuryogan (KBG) and keishibukuryogankayokuinin (KBGY) were the most commonly prescribed Kampo medicines, linked to faster symptom improvement.

  • 4

    Multivariate analysis indicated a significant association between KBG/KBGY use and symptom relief, with a Hazard Ratio of 4.18.

  • 5

    The study highlights the potential of Kampo medicine to enhance quality of life for breast cancer survivors during endocrine therapy.

Original Source(s)

Retrospective Analysis of Kampo Medicine's Role in Mitigating Endocrine Therapy Side Effects in Breast Cancer Patients: A Pilot Investigation

  • by Shin Takayama, Atsuhiko Furuta, Haruhiko Shindo, Ryutaro Arita, Kaolu Sato, Tadashi Ishii

  • February 26, 2026

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