New insights into takotsubo syndrome: results from a multicenter cohort - Takeaways - MDSpire
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Takotsubo Syndrome Revisited: Findings From a Multicenter Cohort Study

  • By

  • Hugo Lanz

  • Endrit Cekaj

  • Lucas Bacmeister

  • Christian Jung

  • Samuel Muli

  • Sabine Hoffmann

  • Matthias Schmid

  • Marcelo Galdos-Bejar

  • Daniel Hoyer

  • Lisa Crusius

  • Norman Mangner

  • Lisa Reinhardt

  • Loubna Yahsaly

  • Lars Michel

  • Victoria Pfeiffer

  • Mostafa Salem

  • Rafael Henrique Rangel

  • Johannes Terporten

  • Fabian Heindl

  • Marcus Brugger

  • Sebastian Zimmer

  • Tienush Rassaf

  • David Leistner

  • Dirk Westermann

  • Benjamin Meder

  • Malte Kelm

  • Stephan Baldus

  • Christian Schulze

  • Georg Nickenig

  • Franz Haertel

  • Enzo Lüsebrink

  • October 19, 2026

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  • 1

    This retrospective multicenter cohort included adults with Takotsubo syndrome treated at 13 German tertiary care centers from 2013 through 2024.

  • 2

    Patients were classified by acute neurologic, other physical, emotional, or unidentified triggers.

  • 3

    The study examined whether acute brain pathology was associated with cardiac dysfunction severity differently from other physical stressors.

  • 4

    Investigators assessed short-term cardiac recovery and factors associated with a critical in-hospital course.

  • 5

    The composite in-hospital cardiac complication endpoint included atrial fibrillation, ventricular tachycardia or fibrillation, pulmonary edema, cardiogenic shock, and death.

Original Source(s)

New insights into takotsubo syndrome: results from a multicenter cohort

  • by Hugo Lanz, Endrit Cekaj, Lucas Bacmeister, Christian Jung, Samuel Muli, Sabine Hoffmann, Matthias Schmid, Marcelo Galdos-Bejar, Daniel Hoyer, Lisa Crusius, Norman Mangner, Lisa Reinhardt, Loubna Yahsaly, Lars Michel, Victoria Pfeiffer, Mostafa Salem, Rafael Henrique Rangel, Johannes Terporten, Fabian Heindl, Marcus Brugger, Sebastian Zimmer, Tienush Rassaf, David Leistner, Dirk Westermann, Benjamin Meder, Malte Kelm, Stephan Baldus, Christian Schulze, Georg Nickenig, Franz Haertel, Enzo Lüsebrink

  • October 19, 2026

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