Impact of Hospice Care Plus Estazolam on Sleep and Psychological Distress in Advanced Gastrointestinal Cancer: A Real-World Observational Study - Takeaways - MDSpire

Effects of Combined Hospice Care and Estazolam on Sleep Quality and Mental Health in Patients with Advanced Gastrointestinal Cancer: A Retrospective Observational Analysis

  • By

  • Hu, Lihong

  • Cao, Donghui

  • Yuan, Xiaoya

  • Wang, Xiangtuan

  • Yuan, Haifeng

  • May 15, 2026

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  • 1

    The study evaluated the effects of hospice care combined with estazolam on sleep quality and mental health in advanced gastrointestinal cancer patients.

  • 2

    A total of 110 inpatients were enrolled, with 59 receiving hospice care plus estazolam and 51 receiving routine nursing plus estazolam.

  • 3

    Significant improvements in sleep quality, anxiety, and depression were observed in the hospice care plus estazolam group after one month.

  • 4

    The hospice care group showed large effect sizes for sleep quality (PSQI), anxiety (SAS), and depression (SDS) compared to the routine nursing group.

  • 5

    The findings indicate that combined hospice care and estazolam significantly enhance sleep, psychological well-being, and quality of life in these patients.

Original Source(s)

Impact of Hospice Care Plus Estazolam on Sleep and Psychological Distress in Advanced Gastrointestinal Cancer: A Real-World Observational Study

  • by Hu, Lihong , Cao, Donghui , Yuan, Xiaoya , Wang, Xiangtuan , Yuan, Haifeng

  • May 15, 2026

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