Clinicopathological characteristics of alveolar adenoma - Takeaways - MDSpire

Clinicopathological characteristics of alveolar adenoma

  • By

  • Jing Chen

  • Zhengjin Liu

  • Wei Zheng

  • Huiling Chen

  • Zeyang Lin

  • Zhe Li

  • June 2, 2026

  • 0 min

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  • 1

    Alveolar adenoma is a rare benign lung tumor characterized by well-defined nodules and typically affects individuals aged 40 to 60.

  • 2

    The tumor is composed of well-differentiated cuboidal or flattened alveolar epithelial cells and a spindle cell stroma.

  • 3

    Immunohistochemical analysis showed strong CD34 expression in stromal cells across all cases, with CD10 positivity in about two-thirds.

  • 4

    The tumors were asymptomatic in the reported cases, with no signs of recurrence or metastasis during follow-up periods.

  • 5

    Further research is needed to explore the nature of alveolar adenoma, particularly through molecular testing of the stromal component.

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