Association of genetic variants with patient reported quality of life and pain experience in patients in the UK NCRI Myeloma X Relapse [Intensive]) trial; an exploratory study - Takeaways - MDSpire

Association of genetic variants with patient reported quality of life and pain experience in patients in the UK NCRI Myeloma X Relapse [Intensive]) trial; an exploratory study

  • By

  • John A. Snowden

  • Sam H. Ahmedzai

  • Angela Cox

  • David A. Cairns

  • A. John Ashcroft

  • Cathy Williams

  • Jamie D. Cavenagh

  • Anna Hockaday

  • Julia M. Brown

  • Ian W. Brock

  • Treen C. M. Morris

  • Gordon Cook

  • June 29, 2022

  • 0 min

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  • 1

    Multiple myeloma is a chronic illness with significant symptom burdens, including pain, fatigue, and impacts on health-related quality of life.

  • 2

    Pain in myeloma arises from both disease progression and treatment side effects, necessitating effective pain management strategies.

  • 3

    The Myeloma X trial demonstrated that salvage autologous stem cell transplant significantly improves survival outcomes compared to conventional treatment.

  • 4

    Patients receiving salvage autologous stem cell transplant reported greater treatment side effects and increased pain for up to two years post-treatment.

  • 5

    The trial provided a unique opportunity to explore genetic factors influencing pain and quality of life in a well-defined population of myeloma patients.

Original Source(s)

Association of genetic variants with patient reported quality of life and pain experience in patients in the UK NCRI Myeloma X Relapse [Intensive]) trial; an exploratory study

  • by John A. Snowden, Sam H. Ahmedzai, Angela Cox, David A. Cairns, A. John Ashcroft, Cathy Williams, Jamie D. Cavenagh, Anna Hockaday, Julia M. Brown, Ian W. Brock, Treen C. M. Morris, Gordon Cook

  • June 29, 2022

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