Effectiveness and safety of carbon ion radiotherapy for stage III non-small cell lung cancer: a single-center retrospective study - Takeaways - MDSpire

Effectiveness and safety of carbon ion radiotherapy for stage III non-small cell lung cancer: a single-center retrospective study

  • By

  • Xiaoli Zhao

  • Bole Wang

  • Yihe Zhang

  • Pengqing Li

  • Xuexue Liang

  • Qinli Gong

  • Ling Tian

  • Tianyan Qin

  • Xuelian Chen

  • Zhenglin Li

  • Peng Nie

  • Yanshan Zhang

  • Yancheng Ye

  • June 30, 2026

  • 0 min

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  • 1

    A retrospective analysis evaluated 82 patients with stage III non-small cell lung cancer treated with carbon ion radiotherapy from March 2020 to March 2024.

  • 2

    The 1-year overall survival, progression-free survival, and local control rates were 85.4%, 79.8%, and 95.3%, respectively.

  • 3

    Adverse events included grade 1 radiation pneumonitis in 6.1% of patients and grade 1 radiation esophagitis in 43.9%.

  • 4

    CIRT combined with immunotherapy was identified as an independent favorable factor for improving overall survival.

  • 5

    The study suggests that CIRT can provide significant survival benefits for stage III NSCLC, with manageable adverse reactions.

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