Frequency of Asymptomatic Meibomian Gland Dysfunction in Adults: A Systematic Review and Meta-Analysis - Takeaways - MDSpire

Frequency of Asymptomatic Meibomian Gland Dysfunction in Adults: A Systematic Review and Meta-Analysis

  • By

  • Zhanar Abu

  • Kairolla Rakhimov

  • Maiya Taushanova

  • Indira Karibayeva

  • April 20, 2026

  • 0 min

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  • 1

    Asymptomatic meibomian gland dysfunction (MGD) is prevalent, with a combined prevalence of 72.86% found in a systematic review of adult populations.

  • 2

    The review included eight studies with 3,637 participants, highlighting significant heterogeneity in prevalence estimates across different studies.

  • 3

    Sensitivity analyses indicated one influential study, but the overall high prevalence of asymptomatic MGD remained consistent.

  • 4

    Meta-regression revealed that sex distribution significantly contributed to variability in prevalence estimates among studies.

  • 5

    The findings suggest that asymptomatic MGD may be an early stage of the disease, emphasizing the need for early identification and preventive measures.

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