Full vs limited FESS tested in CRSwNP

Investigators compare full and limited surgery across patient-reported and clinical outcomes over 24 months.

1

Both full and limited functional endoscopic sinus surgery (FESS) improved disease-specific quality of life in patients with chronic rhinosinusitis with nasal polyps.
2

The study randomized 97 patients with severe, uncontrolled chronic rhinosinusitis with nasal polyps, assessing outcomes at 12 and 24 months.
3

Full FESS showed greater recovery from anosmia and lower nasal polyp scores compared to limited FESS, particularly in the first postoperative year.
4

Improvements in SNOT-22 scores exceeded the minimal clinically important difference, but the between-group difference was not clinically meaningful.
5

The trial's findings may not be generalizable due to limitations, including lack of masking and the specific patient population studied.

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