Early Hip Fracture Surgery Safe in Patients on DOACs - Takeaways - MDSpire

Early Hip Fracture Surgery Safe in Patients on DOACs

Multicenter cohort findings indicate that early surgery in patients on direct oral anticoagulants was associated with shorter hospitalization without increased bleeding.

  • By

  • Julie Greenbaum

  • February 27, 2026

  • 4 min

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  • 1

    Early hip fracture surgery within 24 hours for patients on DOACs is safe and does not lead to greater hemoglobin decrease compared to delayed surgery.

  • 2

    The study analyzed 875 patients aged 70 and older, comparing outcomes of early surgery (n=504) and delayed surgery (n=371) across five trauma centers.

  • 3

    Median hemoglobin decrease was 0.6 mmol/L in the early surgery cohort versus 0.9 mmol/L in the delayed cohort, showing a significant difference.

  • 4

    Early surgery was linked to a shorter hospital stay, with a median of 6 days compared to 8 days for delayed surgery.

  • 5

    No significant differences were found in mortality rates or blood transfusion needs between the early and delayed surgery groups.

Original Source(s)

Early Hip Fracture Surgery Safe in Patients on DOACs

  • by Julie Greenbaum

  • February 27, 2026

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