How to Prevent Rubella Epidemics and Congenital Rubella Syndrome: Lessons From 42 Years of Longitudinal Epidemiology in Osaka Prefecture, Japan (1982–2023) - Takeaways - MDSpire

How to Prevent Rubella Epidemics and Congenital Rubella Syndrome: Lessons From 42 Years of Longitudinal Epidemiology in Osaka Prefecture, Japan (1982–2023)

  • By

  • Daiki Kanbayashi

  • Takako Kurata

  • Yuko Kaida

  • Tatsuya Miyoshi

  • Fumika Okayama

  • Tetsuo Kase

  • Jun Komano

  • Kazuo Takahashi

  • Kazuyoshi Ikuta

  • Kazushi Motomura

  • August 14, 2024

  • 0 min

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  • 1

    Rubella has not been eliminated in Japan despite the introduction of rubella-containing vaccines in 1977.

  • 2

    The shift from selective to universal immunization significantly reduced rubella cases and increased seroprevalence in children.

  • 3

    Rubella resurged in 2012-2013 and 2018-2019, linked to imported virus and susceptible males.

  • 4

    Single-dose vaccination does not fully prevent congenital rubella syndrome and breakthrough infections, necessitating a second dose.

  • 5

    Immunization gaps must be closed to prevent future rubella epidemics and severe outcomes.

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