Liver Supplements: Big Sales, Limited Evidence
Researchers evaluate how popular liver cleanse products are formulated and promoted in the US online marketplace.
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By
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Kathryn Wighton
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January 30, 2026
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Liver cleanse supplements are top sellers on Amazon, promoting detoxification benefits without strong clinical support.
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The study analyzed 20 best-selling liver supplements, revealing high consumer ratings but weak evidence for their claims.
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Estimated annual sales for these supplements exceeded 1.4 million units, generating over $38.8 million in revenue.
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Most products contained ingredients like milk thistle, but only a few showed moderate clinical evidence for efficacy.
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The study emphasizes the need for scrutiny in the liver supplement market due to limited scientific backing despite high sales.