Evaluation of a bidirectional causal association between cardiovascular diseases and pneumonia: a Mendelian randomization study - Takeaways - MDSpire

Evaluation of a bidirectional causal association between cardiovascular diseases and pneumonia: a Mendelian randomization study

  • By

  • Yeshen Zhang

  • Haobin Liu

  • Yining Dai

  • Fei Ye

  • Wenzhi Luo

  • Shan Tu

  • Weikun Chen

  • Siyu Kong

  • Yu He

  • Ning Tan

  • Zhihui Zhang

  • Pengcheng He

  • Yuanhui Liu

  • February 13, 2024

  • 0 min

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  • 1

    This study investigates the bidirectional causal relationship between cardiovascular diseases (CVDs) and pneumonia using Mendelian randomization analysis.

  • 2

    Genetic correlation analysis revealed a significant positive correlation between CVDs and pneumonia, particularly with ischaemic stroke.

  • 3

    Ischaemic stroke was found to have a causal association with various types of pneumonia, including bacterial and pneumococcal pneumonia.

  • 4

    The causal effect of pneumonia on CVDs was not detected, indicating no evidence supporting pneumonia as a risk factor for cardiovascular diseases.

  • 5

    Findings suggest thrombosis risk screening may help reduce pneumonia incidence in patients with ischaemic stroke.

Original Source(s)

Evaluation of a bidirectional causal association between cardiovascular diseases and pneumonia: a Mendelian randomization study

  • by Yeshen Zhang, Haobin Liu, Yining Dai, Fei Ye, Wenzhi Luo, Shan Tu, Weikun Chen, Siyu Kong, Yu He, Ning Tan, Zhihui Zhang, Pengcheng He, Yuanhui Liu

  • February 13, 2024

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