Development of a Comprehensive Program for the Early Diagnosis and Treatment of Severe Infections in a Tertiary Hospital in Spain - Takeaways - MDSpire

Development of a Comprehensive Program for the Early Diagnosis and Treatment of Severe Infections in a Tertiary Hospital in Spain

  • By

  • Guillermo Martín-Gutiérrez

  • José Molina

  • Carlos Martín-Pérez

  • Manuela Aguilar-Guisado

  • María Solla

  • Belén Ramos-Morán

  • Teresa Aldabó

  • Rosario Amaya-Villar

  • Adelina Gimeno

  • Pilar Egea

  • Rocío Álvarez-Marín

  • José Antonio Lepe

  • José Miguel Cisneros

  • September 1, 2025

  • 0 min

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  • 1

    The rDTSI program significantly reduced the median time to pathogen-directed therapy for pneumonia from 48.8 to 23.6 hours.

  • 2

    Targeted therapy within 48 hours increased from 36.17% to 58.14% after the implementation of the rDTSI program.

  • 3

    Hospital stays for patients with severe infections decreased from 38.9 to 22.2 days following the rDTSI program.

  • 4

    In sepsis cases, diagnostic times improved from 19.4 to 18.1 hours, and DOOR-MAT scores increased from 80.4 to 88.0.

  • 5

    The rDTSI program enhanced microbiological diagnosis and optimized antimicrobial therapy, supporting its integration into stewardship programs.

Original Source(s)

Development of a Comprehensive Program for the Early Diagnosis and Treatment of Severe Infections in a Tertiary Hospital in Spain

  • by Guillermo Martín-Gutiérrez, José Molina, Carlos Martín-Pérez, Manuela Aguilar-Guisado, María Solla, Belén Ramos-Morán, Teresa Aldabó, Rosario Amaya-Villar, Adelina Gimeno, Pilar Egea, Rocío Álvarez-Marín, José Antonio Lepe, José Miguel Cisneros

  • September 1, 2025

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