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Imaging markers for diabetic macular oedema: Forecasting visual outcomes beyond retinal thickness

  • By

  • Enrico Borrelli

  • October 18, 2026

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  • 1

    Central subfield thickness explains only a limited fraction of visual acuity variation in diabetic macular oedema.

  • 2

    In a post hoc analysis of 60 KINGFISHER trial eyes, mean visual acuity increased from 62.9 letters at baseline to 75.4 letters at week 52.

  • 3

    Baseline central subfield thickness and a superficial perfusion density and vessel length density index independently predicted week-52 visual acuity.

  • 4

    Greater baseline hyperreflective foci volume was independently associated with a smaller visual acuity gain.

  • 5

    The analysis was limited by optional OCTA acquisition, a single imaging device, modest model variance, and no adjustment for multiple comparisons.

Original Source(s)

Imaging biomarkers in diabetic macular oedema: Predicting vision beyond retinal thickness

  • by Enrico Borrelli

  • October 18, 2026

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