Risk of hypertension and heart failure linked to high-normal serum sodium and tonicity in general healthcare electronic medical records - Takeaways - MDSpire

Risk of hypertension and heart failure linked to high-normal serum sodium and tonicity in general healthcare electronic medical records

  • By

  • Jonathan Rabinowitz

  • Mahmoud Darawshi

  • Nuriel Burak

  • Manfred Boehm

  • Natalia I Dmitrieva

  • April 11, 2025

  • 0 min

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  • 1

    Elevated serum sodium levels are linked to a higher risk of hypertension, with a 29% increase for levels above 143 mmol/L.

  • 2

    Tonicity levels over 287 mosmol/kg are associated with a 19% increased risk of developing hypertension.

  • 3

    The risk of heart failure increases by 20% for serum sodium levels above 143 mmol/L and 15% for tonicity above 289 mosmol/kg.

  • 4

    19% of healthy individuals had serum sodium levels in the 143–146 mmol/L range, indicating potential risk for hypertension and heart failure.

  • 5

    Routine blood tests showing serum sodium of 140 mmol/L or higher may indicate a need for hydration-focused preventive interventions.

Original Source(s)

Risk of hypertension and heart failure linked to high-normal serum sodium and tonicity in general healthcare electronic medical records

  • by Jonathan Rabinowitz, Mahmoud Darawshi, Nuriel Burak, Manfred Boehm, Natalia I Dmitrieva

  • April 11, 2025

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