Prelaminar hyperreflective lines in non-arteritic anterior ischaemic optic neuropathy - Takeaways - MDSpire
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Prelaminar Hyperreflective Lines Associated With Non-Arteritic Anterior Ischaemic Optic Neuropathy

  • By

  • Anas Alkhabaz

  • Bianca Chan

  • Yulan Ren

  • Rishita Rama Pujari

  • Jamie Zhang

  • Hugo Wu

  • Yaping Joyce Liao

  • October 9, 2026

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  • 1

    Among 177 patients with NAION, 42 (23.7%) had ODD-like features on enhanced-depth imaging OCT.

  • 2

    ODD-like features comprised hyperreflective lines in 25 patients and optic disc drusen in 17 patients.

  • 3

    Patients with ODD-like features were more likely to receive a NAION diagnosis before age 50 than those without these features (26% vs 2.2%).

  • 4

    NAION eyes with ODD-like features had better median visual acuity and greater GCC and RNFL thickness than eyes without these features.

  • 5

    Among patients with unilateral NAION and ODD-like features, 88% had ODD or hyperreflective lines in the unaffected fellow eye.

Original Source(s)

Prelaminar hyperreflective lines in non-arteritic anterior ischaemic optic neuropathy

  • by Anas Alkhabaz, Bianca Chan, Yulan Ren, Rishita Rama Pujari, Jamie Zhang, Hugo Wu, Yaping Joyce Liao

  • October 9, 2026

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