Case report: Diffuse large B-cell lymphoma associated with chronic inflammation presenting as a rapidly enlarging perigraft hematoma after TEVAR - Takeaways - MDSpire

Case report: Diffuse large B-cell lymphoma associated with chronic inflammation presenting as a rapidly enlarging perigraft hematoma after TEVAR

  • By

  • Chunxiang Yang

  • Ji Lu

  • Yufei Liu

  • Shuang Li

  • Fanyu Wu

  • July 10, 2026

  • 0 min

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  • 1

    The case involves a patient with diffuse large B-cell lymphoma associated with chronic inflammation following thoracic endovascular aortic repair.

  • 2

    Imaging initially suggested a perigraft hematoma, but the lesion rapidly progressed into a large soft-tissue mass postoperatively.

  • 3

    Core needle biopsy confirmed the diagnosis of Epstein-Barr virus-positive diffuse large B-cell lymphoma with a TP53 mutation.

  • 4

    This case highlights the rarity of DLBCL-CI around vascular grafts, with fewer than five cases reported in the literature.

  • 5

    The study aims to enhance awareness among clinicians to prevent misdiagnosis of this malignancy as a benign lesion.

Original Source(s)

Case report: Diffuse large B-cell lymphoma associated with chronic inflammation presenting as a rapidly enlarging perigraft hematoma after TEVAR

  • by Chunxiang Yang, Ji Lu, Yufei Liu, Shuang Li, Fanyu Wu

  • July 10, 2026

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