Seroprevalence of Dengue, Zika, and Chikungunya Viruses in Humans and Colocated Macaques in Thailand and Cambodia - Takeaways - MDSpire
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Prevalence of Antibodies Against Dengue, Zika, and Chikungunya Viruses in Humans and Nearby Macaques in Thailand and Cambodia

  • By

  • Nanthanida Mongkol

  • Sophana Chea

  • Somnang Man

  • Piseth Ly

  • Cheata Hou

  • Sokna Ly

  • Ratanak Sath

  • Chanthap Lon

  • Kry Hok

  • Huch Chea

  • Rithea Leang

  • Rekol Huy

  • Sophia B Lin

  • Fanny Sae Wang

  • Daraka Tongthainan

  • Wirasak Fungfuang

  • Sudarat Lijitipoom

  • Sarocha Suthisawat

  • Nathamon Kosoltanapiwat

  • Natanon Panpeth

  • Stephen S Whitehead

  • Fabiano Oliveira

  • Rebecca C Christofferson

  • Jessica E Manning

  • Kobporn Boonnak

  • Christina Yek

  • May 21, 2025

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  • 1

    The study assessed seroprevalence of dengue, Zika, and chikungunya viruses in humans and macaques in Thailand and Cambodia from 2019 to 2022.

  • 2

    Higher seropositivity rates were found in human populations (38.5%-74.4%) compared to macaques (0%-8.0%), indicating limited macaque involvement in urban virus cycles.

  • 3

    Virus seroprevalence varied between Thai and Cambodian cohorts, with age being the only significant predictor of human seropositivity.

  • 4

    The study utilized plaque reduction neutralization tests to evaluate seropositivity among 649 humans and 398 macaques across four sites.

  • 5

    Findings suggest that low macaque seropositivity may indicate virus spillback from humans rather than sustained transmission in macaque populations.

Original Source(s)

Seroprevalence of Dengue, Zika, and Chikungunya Viruses in Humans and Colocated Macaques in Thailand and Cambodia

  • by Nanthanida Mongkol, Sophana Chea, Somnang Man, Piseth Ly, Cheata Hou, Sokna Ly, Ratanak Sath, Chanthap Lon, Kry Hok, Huch Chea, Rithea Leang, Rekol Huy, Sophia B Lin, Fanny Sae Wang, Daraka Tongthainan, Wirasak Fungfuang, Sudarat Lijitipoom, Sarocha Suthisawat, Nathamon Kosoltanapiwat, Natanon Panpeth, Stephen S Whitehead, Fabiano Oliveira, Rebecca C Christofferson, Jessica E Manning, Kobporn Boonnak, Christina Yek

  • May 21, 2025

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