Case Report: Pulmonary alveolar adenoma: a case series from a single institution and literature review - Takeaways - MDSpire

Case Report: Pulmonary alveolar adenoma: a case series from a single institution and literature review

  • By

  • Martina Maione

  • Jose Coelho Lima

  • Giuseppe Maggioni

  • Chiara Giraudo

  • Federica Pezzuto

  • Fiorella Calabrese

  • June 29, 2026

  • 0 min

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  • 1

    Alveolar adenomas are rare benign epithelial lung neoplasms, accounting for less than 1% of all pulmonary neoplasms.

  • 2

    Two cases of alveolar adenoma were reported, one mimicking metastasis from breast cancer and the other found incidentally in a young patient.

  • 3

    Histological examination revealed well-circumscribed tumors with cystic spaces lined by cuboidal cells, lacking significant mitotic activity or necrosis.

  • 4

    Immunohistochemical analysis showed positivity for cytokeratins and thyroid transcription factor-1, confirming the alveolar epithelial phenotype.

  • 5

    The incidence of alveolar adenoma at the institution was 0.2%, with approximately seventy cases reported in the literature to date.

Original Source(s)

Case Report: Pulmonary alveolar adenoma: a case series from a single institution and literature review

  • by Martina Maione, Jose Coelho Lima, Giuseppe Maggioni, Chiara Giraudo, Federica Pezzuto, Fiorella Calabrese

  • June 29, 2026

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