Co-infection with Hepatitis Delta Virus in Hepatocellular Carcinoma Patients and HIV-Positive Individuals in Nigeria - Takeaways - MDSpire

Co-infection with Hepatitis Delta Virus in Hepatocellular Carcinoma Patients and HIV-Positive Individuals in Nigeria

  • By

  • Ijeoma Ifeorah

  • Birgit Bremer

  • Yusuf Musa

  • Julia Kahlhöfer

  • Oluwatosin Oguntoye

  • Carey Tishiya

  • Gatuwa Aglavdawa

  • Ojonuga Ameh

  • Yussuf Abdulkadir

  • Olumuyiwa Ariyo

  • Manfred Anim

  • Andre Reinhardt

  • Albert Heim

  • Uwem George

  • Lukman Abdulkareem

  • Ibrahim Umar Garzali

  • Heiner Wedemeyer

  • Lisa Sandmann

  • February 26, 2026

  • 0 min

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  • 1

    Hepatitis D virus (HDV) significantly contributes to liver disease and hepatocellular carcinoma (HCC) in hepatitis B virus (HBV) infected individuals.

  • 2

    Nigeria has a high prevalence of HBV, with an average of 8.1% among adults, creating a substantial risk for HDV infection.

  • 3

    A nationwide study found an anti-HDV prevalence of 4.6% among asymptomatic chronic HBV patients, with regional variations across Nigeria.

  • 4

    HDV remains underdiagnosed in Nigeria due to limited testing and surveillance, hindering effective management and awareness.

  • 5

    The study involved 390 HBsAg-positive participants, including those with advanced liver disease and HIV co-infection, to investigate HDV prevalence.

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