Tracking the longitudinal course of physiologic and mental health functioning among individuals in substance use disorder treatment - Takeaways - MDSpire

Tracking the longitudinal course of physiologic and mental health functioning among individuals in substance use disorder treatment

  • By

  • Wendy Insalaco

  • Charlotte Clapham

  • Brett Gelino

  • Jami Mayo Barney

  • Brianna Billings

  • Jennifer D. Ellis

  • J. Gregory Hobelmann

  • Andrew S. Huhn

  • Vadim Zipunnikov

  • Jill A. Rabinowitz

  • June 10, 2026

  • 0 min

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  • 1

    The study examined the relationship between physiological indicators and self-reported mental health in individuals undergoing SUD treatment.

  • 2

    Participants wore a WHOOP® device to monitor resting heart rate (RHR) and heart rate variability (HRV) during the first month of treatment.

  • 3

    Results showed that 39-42% of participants with decreased RHR and increased HRV reported improvements in stress, anxiety, and depressive symptoms.

  • 4

    Findings indicated significant variability in concurrent changes in physiological and mental health metrics among participants.

  • 5

    The study emphasizes the need for integrating physiological measures with mental health assessments to enhance SUD treatment outcomes.

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