Recurrent Group B Streptococcus Neonatal Invasive Infections, France, 2007–2021 - Takeaways - MDSpire

Recurrent Group B Streptococcus Neonatal Invasive Infections, France, 2007–2021

  • By

  • Ghalia Sbaa

  • Nicolas Delettre

  • Cécile Guyonnet

  • Sébastien Le Huu Nghia

  • Caroline Joubrel-Guyot

  • Céline Plainvert

  • Claire Poyart

  • Asmaa Tazi

  • June 6, 2024

  • 0 min

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  • 1

    A retrospective study identified 1527 cases of GBS neonatal infections in France from 2007 to 2021, with 36 (2.36%) classified as recurrent.

  • 2

    Recurrent infections predominantly affected preterm (68%) and low-birth-weight (72%) infants, linked to hypervirulent GBS clonal complex 17.

  • 3

    No β-lactam–tolerant strains were found, and whole-genome sequencing did not reveal specific features associated with recurrence.

  • 4

    The median interval between initial and recurrent episodes was 22 days, with no infants experiencing a third episode of GBS infection.

  • 5

    The study highlights the need for large-cohort research to optimize management strategies for these uncommon recurrent neonatal infections.

Original Source(s)

Recurrent Group B Streptococcus Neonatal Invasive Infections, France, 2007–2021

  • by Ghalia Sbaa, Nicolas Delettre, Cécile Guyonnet, Sébastien Le Huu Nghia, Caroline Joubrel-Guyot, Céline Plainvert, Claire Poyart, Asmaa Tazi

  • June 6, 2024

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