Evaluating the Efficacy and Safety of Preventive Therapies for Vestibular Migraine: A Systematic Review and Network Meta-Analysis

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Vestibular migraine affects 1–3% of the population and significantly impacts quality of life and healthcare costs.
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The systematic review analyzed preventive treatments for vestibular migraine using network meta-analysis to compare effectiveness.
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Propranolol showed the largest benefits in reducing vertigo attacks, while galcanezumab had the strongest evidence quality and tolerability.
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The analysis emphasizes the need for direct comparison studies between promising treatments for clearer clinical guidance.
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Current treatment approaches for vestibular migraine are largely empirical, lacking specific evidence for effective management.

Bmc Neurology

by Sindhu Vasireddy, Shankar Biswas, Raja Kollu, Elangovan Krishnan, Mohammed Semaal Khan, Fasil C, Arjun Jayakumar, Reena Acharya
December 30, 2025

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