Hepatitis C Co-infection Among Pregnant Women With Syphilis in West Virginia, 2019–2023 - Takeaways - MDSpire

Hepatitis C Co-infection Among Pregnant Women With Syphilis in West Virginia, 2019–2023

  • By

  • Alana G Hudson

  • Bianca Huff

  • Jared Boote

  • Kady Pack

  • Margret Watkins

  • Hanna White

  • Suzanne Wilson

  • Shannon McBee

  • November 21, 2025

  • 0 min

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  • 1

    Among 161 pregnant women with syphilis in West Virginia, 42.9% had a past or present hepatitis C infection.

  • 2

    Women with HCV co-infection reported higher rates of incarceration and drug use compared to those without HCV.

  • 3

    Lower adherence to syphilis treatment was observed in women with HCV, with 56.5% completing treatment versus 84.8% without HCV.

  • 4

    Congenital syphilis outcomes were more frequent in women with HCV, with 59.4% reporting adverse outcomes compared to 28.3% without HCV.

  • 5

    The findings highlight the need for integrated care strategies to address co-infections and associated social vulnerabilities in pregnant women.

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