Underestimation of cardiovascular risk by the SCORE2 model in primary care: a call for recalibration - Takeaways - MDSpire

Underestimation of cardiovascular risk by the SCORE2 model in primary care: a call for recalibration

  • By

  • Vincent M I Voorbrood

  • Arthur M Bohnen

  • Angeline P Bosman

  • Peter R Rijnbeek

  • Dimitris Rizopoulos

  • Patrick J E Bindels

  • April 27, 2025

  • 0 min

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  • 1

    The SCORE2 model predicts cardiovascular event risk but underestimates actual risk in primary care settings.

  • 2

    In a study of 205,548 Dutch patients, the observed 10-year CVE risk was 10.1%, compared to the model's prediction of 6.2%.

  • 3

    The observed-to-expected risk ratios were 1.54 for females and 1.68 for males, indicating significant underestimation.

  • 4

    Approximately 35% of patients may miss preventive treatments due to the SCORE2 model's inaccuracies.

  • 5

    The findings highlight the need for recalibration of the SCORE2 model for more accurate cardiovascular risk assessment.

Original Source(s)

Underestimation of cardiovascular risk by the SCORE2 model in primary care: a call for recalibration

  • by Vincent M I Voorbrood, Arthur M Bohnen, Angeline P Bosman, Peter R Rijnbeek, Dimitris Rizopoulos, Patrick J E Bindels

  • April 27, 2025

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