Chronic Respiratory Disease in the U.S. - Takeaways - MDSpire
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Chronic Respiratory Conditions in the United States: Trends and Future Projections

  • By

  • Debbie Bunch

  • October 20, 2026

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  • 1

    The estimated number of US residents with chronic respiratory disease rose from 33.28 million in 1990 to 54.5 million in 2023.

  • 2

    From 1990 to 2023, age-standardized prevalence increased 10.24%, and age-standardized mortality rose from 19 to 34.56 deaths per 100,000.

  • 3

    Age-standardized mortality declined for asthma and pneumoconiosis but increased for COPD and interstitial lung disease with pulmonary sarcoidosis.

  • 4

    Modifiable risk factors accounted for 44.54% of chronic respiratory disease DALYs; high BMI led asthma burden, smoking led COPD burden, and occupational asthmagen exposure led pneumoconiosis burden.

  • 5

    By 2050, age-standardized prevalence is projected to rise for asthma and interstitial lung disease with pulmonary sarcoidosis, but decline for COPD and pneumoconiosis.

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