Assessment of Global Incidence and Risk Factors for Esophageal, Gastric, and Colorectal Cancers in Adolescents and Young Adults: Insights from the 2021 Global Burden of Disease Study - Takeaways - MDSpire
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Assessment of Global Incidence and Risk Factors for Esophageal, Gastric, and Colorectal Cancers in Adolescents and Young Adults: Insights from the 2021 Global Burden of Disease Study

  • By

  • Huanyu Wei

  • Lei Yuan

  • Yanxia Li

  • Yutong Xia

  • Hongli Miao

  • Xinrui Xu

  • Linfei Li

  • Lei Shen

  • Mengyao Ji

  • October 31, 2025

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  • 1

    Colorectal cancers are the third most prevalent cancer globally, accounting for 9.6% of new cases in 2022.

  • 2

    The burden of esophageal, stomach, and colorectal cancers has increased significantly among adolescents and young adults.

  • 3

    The GBD 2021 database provides comprehensive epidemiological data on digestive tract cancers across 204 countries from 1990 to 2021.

  • 4

    Socioeconomic development levels, measured by the SDI, correlate with the incidence and mortality rates of these cancers.

  • 5

    Key risk factors for digestive tract cancers include alcohol use, dietary risks, tobacco, and high body mass index.

Original Source(s)

Assessment of Global Incidence and Risk Factors for Esophageal, Gastric, and Colorectal Cancers in Adolescents and Young Adults: Insights from the 2021 Global Burden of Disease Study

  • by Huanyu Wei, Lei Yuan, Yanxia Li, Yutong Xia, Hongli Miao, Xinrui Xu, Linfei Li, Lei Shen, Mengyao Ji

  • October 31, 2025

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