Intra-articular steroid injections for lumbar disk herniation: a systematic review and meta-analysis - Takeaways - MDSpire

Intra-articular steroid injections for lumbar disk herniation: a systematic review and meta-analysis

  • By

  • Saran Singh Gill

  • Pratik Ramkumar

  • Abith Ganesh Kamath

  • Sreeraag Kanakala

  • Akhil Anil

  • Srikar Reddy Namireddy

  • Srihan Yalavarthy

  • Daniele S. C. Ramsay

  • Ahmed Salih

  • Ahkash Thavarajasingam

  • Adrisa Prashar

  • Sajeenth Vishnu K

  • Tim Beutel

  • Salvatore Russo

  • Santhosh G. Thavarajasingam

  • Hariharan Subbiah Ponniah

  • November 14, 2025

  • 0 min

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  • 1

    Lumbar disc herniation (LDH) affects 5–20 individuals per 1,000 annually, with higher prevalence in males aged 30–50 years.

  • 2

    Intra-articular steroid injections, including TFESI, IESI, and CESI, provide effective symptomatic relief for patients with LDH.

  • 3

    These steroid injections reduce inflammation and pain by inhibiting pro-inflammatory cytokines and decreasing pain mediators.

  • 4

    This systematic review and meta-analysis evaluates the efficacy of different IA steroid injection techniques for LDH management.

  • 5

    The study aims to support evidence-based recommendations to improve pain management and functional outcomes for LDH patients.

Original Source(s)

Intra-articular steroid injections for lumbar disk herniation: a systematic review and meta-analysis

  • by Saran Singh Gill, Pratik Ramkumar, Abith Ganesh Kamath, Sreeraag Kanakala, Akhil Anil, Srikar Reddy Namireddy, Srihan Yalavarthy, Daniele S. C. Ramsay, Ahmed Salih, Ahkash Thavarajasingam, Adrisa Prashar, Sajeenth Vishnu K, Tim Beutel, Salvatore Russo, Santhosh G. Thavarajasingam, Hariharan Subbiah Ponniah

  • November 14, 2025

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