Uncommon Case of Disseminated Talaromyces marneffei Infection Manifesting as Acute Pancreatitis in a Patient with HIV-1 - Takeaways - MDSpire

Uncommon Case of Disseminated Talaromyces marneffei Infection Manifesting as Acute Pancreatitis in a Patient with HIV-1

  • By

  • Yanqi Peng

  • Mi Zhang

  • Dandan Yang

  • Yuanlu Shu

  • Jincheng Lou

  • Hongli Fan

  • Zhenglun Li

  • Suyun Lei

  • Xingqi Dong

  • Li Gao

  • December 23, 2025

  • 0 min

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  • 1

    Talaromyces marneffei is a life-threatening fungus primarily affecting immunocompromised individuals in Southeast Asia.

  • 2

    Acute pancreatitis is a rare complication of fungal infections, with Talaromyces marneffei-associated cases previously undocumented.

  • 3

    The presented case involves a 52-year-old man with HIV-1/AIDS who developed acute pancreatitis due to Talaromyces marneffei.

  • 4

    Despite antifungal treatment, the patient's condition worsened, leading to septic shock and multiple organ failure.

  • 5

    The patient's irregular use of ART contributed to poor immune reconstitution, making him susceptible to opportunistic infections.

Original Source(s)

Uncommon Case of Disseminated Talaromyces marneffei Infection Manifesting as Acute Pancreatitis in a Patient with HIV-1

  • by Yanqi Peng, Mi Zhang, Dandan Yang, Yuanlu Shu, Jincheng Lou, Hongli Fan, Zhenglun Li, Suyun Lei, Xingqi Dong, Li Gao

  • December 23, 2025

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