Editorial: Long COVID and its biomedical dimensions

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The Special Issue presents five studies examining Long COVID through pulmonary imaging, carotid body morphology, serological biomarkers, and microbiota-directed treatment.
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In survivors of severe COVID-19 ARDS, reticulations or septal thickening correlated with dyspnoea, while parenchymal or atelectatic bands were associated with reduced forced vital capacity.
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Ultra-low-dose CT showed 95.0% diagnostic accuracy for persistent lung abnormalities after moderate to severe COVID-19 pneumonia, increasing to 98% in non-obese patients.
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Among 275 patients with Omicron-related Long COVID, lower spike antibody titers correlated with memory impairment and poorer quality of life, while nucleocapsid titers correlated with acute severity.
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A randomized, double-blind, placebo-controlled trial found that 4 weeks of probiotics reduced fatigue scores more than placebo, although the authors cautioned that the sample was limited.

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