Protocol for the MpoxCARE Study: A Comprehensive Evaluation of Immunization Strategies During Emergency Outbreaks of Mpox - Takeaways - MDSpire

Protocol for the MpoxCARE Study: A Comprehensive Evaluation of Immunization Strategies During Emergency Outbreaks of Mpox

  • By

  • Karishma Gokani

  • Herve Semukunzi

  • Gilbert Rukundo

  • Jenny Clarke

  • Sian E. Faustini

  • Jean Pierre Musabyimana

  • Siobhan Roche

  • Scott Jones

  • Ashley David Otter

  • Alex Richter

  • Claude Muvunyi

  • Jennifer Heaney

  • Christopher Aird Green

  • February 13, 2026

  • 0 min

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  • 1

    Mpox is caused by the human Monkeypox virus, primarily transmitted through close contact with infected animals or humans.

  • 2

    The 2022 outbreak prompted the WHO to declare a public health emergency, with significant case numbers reported in the Democratic Republic of Congo.

  • 3

    Three vaccines are recommended by the WHO for Mpox prevention, with vaccination advised for high-risk individuals and as post-exposure prophylaxis.

  • 4

    The MpoxCARE study aims to validate immunodiagnostic assays for detecting Mpox-specific antibodies in Rwanda and assess vaccine cold-chain capabilities.

  • 5

    Rwanda's robust public health infrastructure and low case numbers make it an ideal setting for the study, which could inform broader regional vaccination strategies.

Original Source(s)

Protocol for the MpoxCARE Study: A Comprehensive Evaluation of Immunization Strategies During Emergency Outbreaks of Mpox

  • by Karishma Gokani, Herve Semukunzi, Gilbert Rukundo, Jenny Clarke, Sian E. Faustini, Jean Pierre Musabyimana, Siobhan Roche, Scott Jones, Ashley David Otter, Alex Richter, Claude Muvunyi, Jennifer Heaney, Christopher Aird Green

  • February 13, 2026

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