Clinical Course of COVID-19 in Children With Adrenal Insufficiency: Results From National Data - Takeaways - MDSpire

Clinical Course of COVID-19 in Children With Adrenal Insufficiency: Results From National Data

  • By

  • Donatella Capalbo

  • Cristina Moracas

  • Laura Guazzarotti

  • Federico Baronio

  • Marianna Rita Stancampiano

  • Rita Ortolano

  • Mariella Valenzise

  • Carla Bizzarri

  • Giuseppa Patti

  • Silvia Longhi

  • Claudia Giavoli

  • Chiara Guzzetti

  • Silvia Zoletto

  • Crescenza Lattanzio

  • Paolo Cavarzere

  • Maria Elisabeth Street

  • Maria Felicia Faienza

  • Anna Grandone

  • Marco Cappa

  • Malgorzata Gabriela Wasniewska

  • Gianni Russo

  • Mohamad Maghnie

  • Mariacarolina Salerno

  • On behalf of the Study Group for Adrenal Diseases of the Italian Society for Pediatric Endocrinology and Diabetes

  • February 7, 2025

  • 0 min

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  • 1

    In a study of 1143 children with adrenal insufficiency (AI), 148 contracted COVID-19, showing a prevalence of 12.9%.

  • 2

    The severity of COVID-19 in children with AI was not increased compared to controls, with similar rates of asymptomatic and mild cases.

  • 3

    Among severe cases, 4 patients with AI and 3 controls developed pneumonia, while 3 AI patients and 2 controls had multisystem inflammatory syndrome.

  • 4

    Only 5 patients (3.4%) experienced an adrenal crisis during severe COVID-19, and hospitalization rates were identical between AI patients and controls.

  • 5

    The study concluded that adrenal insufficiency does not increase susceptibility to SARS-CoV-2 infection or risk for severe COVID-19 in children.

Original Source(s)

Clinical Course of COVID-19 in Children With Adrenal Insufficiency: Results From National Data

  • by Donatella Capalbo, Cristina Moracas, Laura Guazzarotti, Federico Baronio, Marianna Rita Stancampiano, Rita Ortolano, Mariella Valenzise, Carla Bizzarri, Giuseppa Patti, Silvia Longhi, Claudia Giavoli, Chiara Guzzetti, Silvia Zoletto, Crescenza Lattanzio, Paolo Cavarzere, Maria Elisabeth Street, Maria Felicia Faienza, Anna Grandone, Marco Cappa, Malgorzata Gabriela Wasniewska, Gianni Russo, Mohamad Maghnie, Mariacarolina Salerno, On behalf of the Study Group for Adrenal Diseases of the Italian Society for Pediatric Endocrinology and Diabetes

  • February 7, 2025

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