Systematic review, meta-analysis of cusp-overlap vs. three-cusp coplanar approaches in self-expandable transcatheter aortic valve replacement - Takeaways - MDSpire

Systematic review, meta-analysis of cusp-overlap vs. three-cusp coplanar approaches in self-expandable transcatheter aortic valve replacement

  • By

  • Mohammad Ghannam

  • Mustafa Abomohsen

  • Iyad Y. Idries

  • Fayez Shamoon

  • Rahul Vasudev

  • Khaled Moghib

  • Muhammad Ghallab

  • Fawzi Zghyer

  • Alena V. González

  • Abdullah Ahmad

  • Habib A. Habib

  • July 2, 2026

  • 0 min

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  • 1

    The cusp-overlap technique (COT) may improve implantation depth and reduce conduction disturbances in transcatheter aortic valve replacement (TAVR).

  • 2

    COT significantly reduced mortality compared to the standard three-cusp technique (ST), with the strongest effect observed at 30 days post-procedure.

  • 3

    COT was associated with lower rates of conduction disturbances and permanent pacemaker implantation compared to ST.

  • 4

    There was no significant difference in cerebrovascular accidents between the cusp-overlap technique and the standard three-cusp technique.

  • 5

    The systematic review included 18 studies, analyzing outcomes across varying patient populations and highlighting the need for further randomized studies.

Original Source(s)

Systematic review, meta-analysis of cusp-overlap vs. three-cusp coplanar approaches in self-expandable transcatheter aortic valve replacement

  • by Mohammad Ghannam, Mustafa Abomohsen, Iyad Y. Idries, Fayez Shamoon, Rahul Vasudev, Khaled Moghib, Muhammad Ghallab, Fawzi Zghyer, Alena V. González, Abdullah Ahmad, Habib A. Habib

  • July 2, 2026

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