A prediction model and risk stratification tool for survival by chemotherapy in invasive micropapillary carcinoma of the breast: a population-based study with external validation - Takeaways - MDSpire

A prediction model and risk stratification tool for survival by chemotherapy in invasive micropapillary carcinoma of the breast: a population-based study with external validation

  • By

  • Fang Yang

  • Yiqi Yang

  • Qiuping Xu

  • Lin Tang

  • Yucai Wang

  • Elizabeth J. Cathcart-Rake

  • Li Xie

  • June 4, 2026

  • 0 min

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  • 1

    Invasive micropapillary carcinoma (IMPC) of the breast shows a high risk for lymphovascular invasion and lymph node metastasis.

  • 2

    Chemotherapy significantly improves overall survival in high-risk IMPC patients but not in low-risk patients.

  • 3

    A risk stratification model was developed to identify IMPC patients most likely to benefit from chemotherapy.

  • 4

    The study utilized data from the SEER database and an external validation cohort to confirm findings.

  • 5

    Clinical decisions regarding chemotherapy for IMPC should consider individual risk assessments based on various factors.

Original Source(s)

A prediction model and risk stratification tool for survival by chemotherapy in invasive micropapillary carcinoma of the breast: a population-based study with external validation

  • by Fang Yang, Yiqi Yang, Qiuping Xu, Lin Tang, Yucai Wang, Elizabeth J. Cathcart-Rake, Li Xie

  • June 4, 2026

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