CT-derived density of intracranial arteriosclerosis: a population-based cohort study - Takeaways - MDSpire

CT-derived density of intracranial arteriosclerosis: a population-based cohort study

  • By

  • Bernhard P. Berghout

  • Robin Y. R. Camarasa

  • Maarten J. G. Leening

  • Marleen de Bruijne

  • M. Kamran Ikram

  • Daniel Bos

  • January 15, 2026

  • 0 min

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  • 1

    Intracranial artery calcification (IAC) is a significant risk factor for stroke and dementia, highlighting its clinical importance.

  • 2

    The study investigates the density of IAC, which may provide additional insights into the stability of atherosclerotic disease.

  • 3

    Current literature lacks comprehensive data on IAC density, primarily focusing on volume rather than density or determinants.

  • 4

    Distinct morphological patterns of IAC, medial and intimal calcifications, have different associations with cardiovascular risk factors.

  • 5

    The Rotterdam Study provides a robust population-based framework to analyze IAC density and its determinants among older adults.

Original Source(s)

CT-derived density of intracranial arteriosclerosis: a population-based cohort study

  • by Bernhard P. Berghout, Robin Y. R. Camarasa, Maarten J. G. Leening, Marleen de Bruijne, M. Kamran Ikram, Daniel Bos

  • January 15, 2026

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