Response to “Left Ventricular Longitudinal Function and Hyperkinetic Profile: A New Echocardiographic Area for Exploration?”

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In exploratory post hoc analyses, 90-day mortality was 27% with LVEF >70% and 23% with LVEF 50%–70%, with no significant adjusted difference.
2

Patients with LVEF >70% had greater absolute GLS magnitude and modestly higher MAPSE than those with LVEF 50%–70%; S′ did not differ significantly.
3

No distinct MAPSE, GLS, or S′ threshold corresponding to a hyperdynamic LVEF profile was identified.
4

High-value GLS, MAPSE, and S′ groups were not associated with 90-day mortality in unadjusted or adjusted analyses.
5

The exploratory findings suggest hyperdynamic LVEF may not reflect a comparably hyperdynamic longitudinal systolic profile and warrant cautious interpretation.

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