Global Prevalence of Long COVID, Its Subtypes, and Risk Factors: An Updated Systematic Review and Meta-analysis - Takeaways - MDSpire

Global Prevalence of Long COVID, Its Subtypes, and Risk Factors: An Updated Systematic Review and Meta-analysis

  • By

  • Yiren Hou

  • Tian Gu

  • Zhouchi Ni

  • Xu Shi

  • Megan L Ranney

  • Bhramar Mukherjee

  • August 30, 2025

  • 0 min

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  • 1

    The global pooled prevalence of long COVID is 36%, with the highest rates observed in South America at 51%.

  • 2

    Long COVID symptoms persist over time, with 35% prevalence at less than 1 year and 46% at 1-2 years post-infection.

  • 3

    The most common long COVID subtypes include respiratory symptoms and general fatigue, each at 20% prevalence.

  • 4

    Key risk factors for long COVID include being unvaccinated, infections from pre-Omicron variants, and female sex.

  • 5

    The study highlights the need for well-designed follow-up studies to address the heterogeneity of long COVID estimates.

Original Source(s)

Global Prevalence of Long COVID, Its Subtypes, and Risk Factors: An Updated Systematic Review and Meta-analysis

  • by Yiren Hou, Tian Gu, Zhouchi Ni, Xu Shi, Megan L Ranney, Bhramar Mukherjee

  • August 30, 2025

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