Surgical treatment of multiple breast cancer brain metastases: clinical characteristics and factors impacting postoperative survival - Takeaways - MDSpire

Surgical treatment of multiple breast cancer brain metastases: clinical characteristics and factors impacting postoperative survival

  • By

  • Anna Michel

  • Laurèl Rauschenbach

  • Hanah Karadachi

  • Meltem Gümüs

  • Yahya Ahmadipour

  • Marvin Darkwah Oppong

  • Christoph Pöttgen

  • Jörg Hense

  • Neriman Özkan

  • Karsten H. Wrede

  • Philipp Dammann

  • Ulrich Sure

  • Ramazan Jabbarli

  • April 29, 2025

  • 0 min

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  • 1

    Breast cancer brain metastases (BCBM) significantly impact morbidity and mortality, with incidence varying from 15% to 50% based on cancer subtype.

  • 2

    Median overall survival after BCBM surgery ranges from 6 to 18 months, influenced by factors like the number of metastases and tumor subtype.

  • 3

    Surgical treatment for multiple BCBM remains controversial, though resection may prolong survival even in cases with multiple metastases.

  • 4

    The study analyzed 93 patients with metachronous BCBM, comparing outcomes between those with single and multiple brain metastases.

  • 5

    Key factors associated with multiple BCBM include negative progesterone receptor status, infratentorial localization, and hepatic metastases.

Original Source(s)

Surgical treatment of multiple breast cancer brain metastases: clinical characteristics and factors impacting postoperative survival

  • by Anna Michel, Laurèl Rauschenbach, Hanah Karadachi, Meltem Gümüs, Yahya Ahmadipour, Marvin Darkwah Oppong, Christoph Pöttgen, Jörg Hense, Neriman Özkan, Karsten H. Wrede, Philipp Dammann, Ulrich Sure, Ramazan Jabbarli

  • April 29, 2025

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