Lung microvasculopathy in chronic thromboembolic pulmonary hypertension: high-resolution findings with photon-counting detector CT in 29 patients - Takeaways - MDSpire

Lung microvasculopathy in chronic thromboembolic pulmonary hypertension: high-resolution findings with photon-counting detector CT in 29 patients

  • By

  • Martine Remy-Jardin

  • Alain Duhamel

  • Marie Delobelle

  • Jean-François Bervar

  • Thomas Flohr

  • Jacques Remy

  • April 18, 2025

  • 0 min

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  • 1

    Chronic thromboembolic pulmonary hypertension (CTEPH) results from unresolved clots and small-vessel arteriopathy in pulmonary arteries.

  • 2

    Small-vessel arteriopathy contributes to elevated pulmonary vascular resistance and residual pulmonary hypertension after pulmonary thromboendarterectomy.

  • 3

    High-resolution photon-counting detector CT (PCD-CT) can detect subtle morphological changes in lung microcirculation in CTEPH patients.

  • 4

    The study involved 29 CTEPH patients with confirmed pulmonary hypertension and a mosaic perfusion pattern observed on chest CTA.

  • 5

    Mosaic perfusion patterns on CT highlight areas of hypo- and hyperperfusion, indicating potential small-vessel disease in CTEPH.

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